Dexamethasone: A Brief History:
Dexamethasone is a corticosteroid medication that has been widely used for over six decades. Here's a brief overview of its history:


  • 1950s: Dexamethasone was first synthesized in the 1950s by a team of scientists at the American pharmaceutical company, Upjohn.
  • 1961: The US FDA approved dexamethasone for use in humans, and it was first marketed as a prescription medication under the brand name Decadron.
  • 1960s-1970s: Dexamethasone became widely used for its anti-inflammatory and immunosuppressive properties, particularly in the treatment of rheumatoid arthritis, asthma, and skin conditions.
  • 1980s: Its use expanded to include the treatment of certain cancers, such as leukemia and lymphoma.
  • 2020: Dexamethasone gained significant attention for its role in reducing the severity of COVID-19 symptoms, particularly in severe cases.
Today, dexamethasone remains a widely used medication, available in various formulations, including tablets, injections, and topical creams. Its versatility and efficacy have made it a staple in the medical community.


Dexamethasone use Treatment:


Dexamethasone is used to treat a wide range of conditions, including 
  • Rheumatic problems: Dexamethasone is used to treat conditions such as rheumatoid arthritis.
  • Skin diseases:It is used to treat various skin conditions.
  • Allergies: Dexamethasone is used to treat severe allergic reactions.
  • Asthma: It is used to treat asthma and other respiratory conditions.
  • Eye pain: It is used to treat eye pain following eye surgery.
  • Brain swelling: Dexamethasone is used to treat brain swelling.
  • Tuberculosis: It is used to treat tuberculosis, along with antibiotics.
  • Croup: A single dose of dexamethasone can reduce the swelling of the airway and improve breathing in croup.
  • Plantar fasciitis: It is injected into the heel to treat plantar fasciitis.
  • Anaphylactic shock: Dexamethasone is used to counteract allergic anaphylactic shock.
  • Cancer: It is used as a chemotherapeutic agent in certain hematological malignancies, such as multiple myeloma.
  • High-altitude illnesses: Dexamethasone is used to treat high-altitude cerebral edema and high-altitude pulmonary edema.
  • Nausea and vomiting: It is effective in preventing nausea and vomiting in people who have had surgery.
  • Sore throat: A single dose of dexamethasone can speed up the improvement of a sore throat.
  • COVID-19: Dexamethasone is recommended for people with COVID-19 who need mechanical ventilation or supplemental oxygen.



Dexamethasone side effects include:
  • Weight gain
  • Indigestion
  • Sleep problems
  • Mild mood changes
  • Acne
  • Amnesia
  • Birth defect
  • Cataract
  • Confusion
  • Depression
  • Dyspepsia
  • Euphoria
  • Headaches
  • Hiccups
  • Hyperglycemia
  • Hypertension
  • Impaired skin healing and wound repair
  • Increased appetite
  • Insomnia
  • Irritability
  • Malaise
  • Osteoporosis
  • Nausea
  • Vomiting
  • Muscle atrophy and myopathy
  • Ocular hypertension
  • Vertigo
  • Allergic reactions
  • High doses may cause psychiatric symptoms like anxiety, insomnia, mania or delirium

Dexamethasone use Medican name:
Dexamethasone is sold under various brand names, including:
  • Decadron
  • Dexone
  • Dexasone
  • Dexasporin
  • Ozurdex
  • Baycadron
  • Dexacen
  • Dexacort
  • Dexa-Cortidin
  • Dexa-Rhinospray
  • Dexa-Scheroson
  • Dexaforte
  • Dextenza
It's also available in generic form and in various combinations with other medications.
Please note that the availability of these brand names may vary depending on your location and country.