History:

Here's a brief history of ibuprofen 

  • In 1953, chemist John Nicholson and pharmacist Stewart Adams began searching for a version of aspirin that could be used long-term for rheumatoid arthritis at Boots Pure Drug Company Ltd.
  • In 1961, Adams and Nicholson discovered the compound 2-(4-isobutylphenyl) propionic acid, later to be called ibuprofen, after screening over 600 candidates.
  • In 1966, six patients with rheumatoid arthritis were involved in clinical trials of ibuprofen, which were held in Edinburgh.
  • Ibuprofen was introduced in the UK in 1969 for the treatment of rheumatic illnesses and was marketed as the prescription medication Brufen.
  • In the 1970s, Brufen pills were given a product license.
  • Ibuprofen became available in the United States in 1974, and was prescribed for rheumatoid arthritis.
  • In 1983, the UK approved ibuprofen as an over-the-counter medicine.
  • In 1985, generic versions of ibuprofen became available when the Boots worldwide patent for ibuprofen expired.
  • By 1985, more than 100 million people in 120 countries had received ibuprofen, and Boots received the Queen's Award for Technological Achievement for discovering ibuprofen.
  • In 1996, ibuprofen was made available without a prescription.

Here are some side effects of ibuprofen :
  • Nausea
  • Indigestion
  • Headache
  • Dizziness
  • Diarrhea
  • Constipation
  • Gastrointestinal ulceration
  • Rash
  • Salt and fluid retention
  • High blood pressure
  • Heartburn
  • Stomach pain
  • Ulcers in the stomach or gut
  • Allergic reactions
  • Asthma
  • Heart failure
  • Kidney failure
  • Liver failure
    It's important to consult with a medical professional if any of these side effects worsen or if you have any other concerns.

Ibuprofen is used for the treatment:
  • Fever
  • Mild to moderate pain
  • Painful menstruation
  • Osteoarthritis
  • Dental pain
  • Headaches
  • Rheumatoid arthritis
  • Pain from kidney stones
  • Lower back pain
  • Inflammatory diseases, such as juvenile idiopathic arthritis
  • Pericarditis
  • Patent ductus arteriosus
  • Acne
  • Orthostatic hypotension
    It's important to consult with a medical professional if any of these conditions worsen or if you have any other concerns.
Dosing: